Return to Directory

Desiree Wanders, PhD

Undergraduate Program Director and Assistant Professor    
Education

PhD in Biomedical Sciences from Auburn University

Biography

Research Interests
Nutritional and pharmacological interventions to prevent or treat obesity and metabolic disease, white and brown adipose tissue remodeling, adipose tissue physiology, regulation of energy balance, inflammation and metabolic disease.

Scholarship publications, funding, podium presentations for past 2-3 years

5P20GM103528-09 NIH/NIGMS Centers of Biomedical Research Excellence. “Mentoring Obesity and Diabetes Research in Louisiana”.
March 2015- Role: Project Principal Investigator

1 F32 DK098918-01A1 NIH Ruth L. Kirschstein National Research Service Award: F32. “Role of UCP1 in the Inter-organ Lipid Cycle Engaged by Dietary Methionine Restriction”.
January 2014- February 2015 Role: Principal Investigator

7-13-MI-05 American Diabetes Association Mentor-Based Postdoctoral Minority Fellowship Award. Role of UCP1 in the Inter-organ Lipid Cycle Engaged by Dietary Methionine Restriction.
October 2013- December 2013. Role: Postdoctoral Fellow

Keystone Symposia Future of Science Fund Scholarship (Travel Grant)
Keystone Symposia – Beige and Brown Fat: Basic Biology and Novel Therapeutics
April 2015

3T32DK064584 NIH Ruth L. Kirschstein National Research Service Award: Institutional Research Training Grant (T32). “Obesity: From Genes to Man”, Pennington Biomedical Research Center
October 2012- September 2013. Role: Postdoctoral Fellow

Selected Publications

  1. Stone KP, Wanders D, Calderon LF, Spurgin SB, Scherer PE, Gettys TW (2015). Compromised responses to dietary methionine restriction in adipose tissue but not liver of ob/ob mice. Obesity.-In Press.
  2. Wanders D, Burk DH, Cortez CC, Van NT, Stone KP, Baker M, Mendoza T, Mynatt RL, Gettys TW (2015). UCP1 is an essential mediator of the effects of methionine restriction on energy balance but not insulin sensitivity. The FASEB Journal. 29(6):2603-2615.
  3. Godwin LA, Brooks JC, Hoepfner LD, Wanders D, Judd RL, Easley CJ (2015). A microfluidic interface design for the culture and sampling of adiponectin from primary adipocytes. Analyst. 140(4):1019-1025.
  4. Stone KP, Wanders D, Orgeron M, Cortez CC, Gettys TW (2014). Mechanisms of increased in vivo insulin sensitivity by dietary methionine restriction in mice. Diabetes. 63(11):3721-3733.
  5. Wanders D, Ghosh S, Stone KP, Van NT, Gettys TW (2014). Transcriptional impact of dietary methionine restriction on systemic inflammation: relevance to biomarkers of metabolic disease during aging. BioFactors.40(1):13-26.
  6. Ghosh S, Wanders D, Stone KP, Van NT, Cortez CC, Gettys TW (2014). A systems biology analysis of the unique and overlapping transcriptional responses to caloric restriction and dietary methionine restriction in rats. FASEB Journal. 28(6):2577:2590.
  7. Nanjappa MK, Ahuja M, Dhanasekaran M, Coleman ES, Braden TD, Bartol FF, Bird RC, Wanders D, Judd RL, Akingbemi BT (2013). Bisphenol A regulation of testicular endocrine function in male rats is affected by diet. Toxicology Letters. 225(3):479-487.
  8. Wanders D, Graff EC, White, BD, Judd RL (2013). Niacin increases adiponectin and decreases adipose tissue inflammation in high fat diet-fed mice. PLOS ONE. 8(8):e71285.
  9. Hasek B, Boudreau A, Shin J, Feng D, Hulver M, Van NT, Laque A, Stewart L, Stone KP, Wanders D, Ghosh S, Pessin J, Gettys TW (2013). Remodeling the integration of lipid metabolism between liver and adipose tissue by dietary methionine restriction in rats. Diabetes. 62(10):3362-3372.
  10. Wanders D, Graff EC, Judd RL (2012). Effects of high fat diet on GPR109A and GPR81 expression in the adipose tissue. Biochemical and Biophysical Research Communications. 425(2):278-283.
  11. Pfhaeler A, Nanjappa MK, Coleman ES, Mansour M, Wanders D, Plaisance EP, Judd RL, Akingbemi BT (2012). Regulation of adiponectin secretion by soy isoflavones has implication for endocrine function of the testis. Toxicology Letters. 209(1):78-85.
  12. Wanders D, Judd RL (2011). Future of GPR109A agonists in the treatment of dyslipidaemia. Diabetes, Obesity and Metabolism. 13(8):685-691.
  13. Godwin LA, Pilkerton ME, Deal KS, Wanders D, Judd RL, Easley CJ (2011). A passively operated microfluidic device for stimulation and secretion sampling of single pancreatic islets. Analytical Chemistry. 83(18):7166-72.
  14. Gropper SS, Clary K, Gaines A, Wanders D, Simmons K (2011). Summer doesn’t reverse freshman year body weight and fat gains in female college students. The Open Nutrition Journal. 5:24-31.
  15. Wanders D, Plaisance EP, Judd RL (2010). Pharmacological effects of lipid-lowering drugs on circulating adipokines. World Journal of Diabetes. 1(4):116-28.
  16. Gropper SS, Simmons KP, Gaines A, Drawdy K, Saunders D, Ulrich P, Connell LJ (2009). The freshman 15 – a closer look. Journal of American College Health. 58(3):223-31.
  17. Orgeron ML, Stone KP, Wanders D, Cortez CC, Van NT, Gettys TW (2014). The impact of dietary methionine restriction on biomarkers of metabolic health. Progress in Molecular Biology and Translational Science. 121:351-376.
  18. Wanders D, Plaisance EP, Judd RL (2012). Lipid-lowering drugs and circulating adiponectin. Adiponectin. Vitamins and Hormones, Volume 90: Toluca Lake, CA.

Selected Presentations

  1. Wanders D, Burk DH, Gettys TW. Dietary restriction of essential amino acids induces browning of white adipose tissue. Keystone Symposia on Beige and Brown Fat: Basic Biology and Novel Therapeutics. Snowbird, Utah, April 2015.
  2. Wanders D, Stone KP, Cortez CC, Burk DH, Orgeron M, Dille K, Gettys TW. Effects of dietary leucine restriction on energy balance and insulin sensitivity. 8th Annual Boshell Diabetes and Metabolic Diseases Research Day. Auburn, AL, February 2015.
  3. Wanders D, Cortez CC, Van NT, Stone KP, Baker M, Burk DH, Mendoza T, Mynatt RL, Gettys TW. Effects of dietary methionine restriction on energy balance: Roles of UCP1 and FGF21. 7th Annual Boshell Diabetes and Metabolic Diseases Research Day. Auburn, AL, February 2014.
  4. Wanders D, Van NT, Gettys TW. Dietary methionine restriction attenuates the development of age-associated inflammation. 6th Annual Boshell Diabetes and Metabolic Diseases Research Day. Auburn, AL, March 2013.
  5. Wanders D, Graff EC, White BD, Judd RL. Niacin increases adiponectin and decreases markers of adipose tissue inflammation in obese mice. 6th Annual Boshell Diabetes and Metabolic Diseases Research Day. Auburn, AL, March 2013.
  6. Wanders D, Graff EC, Plaisance EP, Judd RL. Niacin increases adiponectin in obese mice in a receptor-dependent manner. American Diabetes Association 72nd Scientific Sessions. Philadelphia, PA, June 2012.
  7. Wanders D, Graff EC, Plaisance EP, Judd RL. Niacin increases adiponectin in obese mice in a receptor-dependent manner. 5th Annual Boshell Diabetes and Metabolic Diseases Research Day. Auburn, AL, March 2012.
  8. Wanders D, Plaisance, EP, Graff EC, Zhang Y, Cao G, Judd RL. Mechanism of action of niacin on adiponectin production and secretion. 4th Annual Boshell Diabetes and Metabolic Diseases Research Day. Auburn, AL, March 2011.
  9. Plaisance EP, Hanson LD, Saunders D, Graham T, Lukasova M, Offermanns S, Judd RL. Niacin decreases serum retinol binding protein 4 (RBP4) concentrations in humans with metabolic syndrome. American Diabetes Association 69th Scientific Sessions. New Orleans, LA. Late Breaking Abstract 70-LB, June 2009.
  10. Gropper SS, Saunders D, Gaines A, Simmons K, Connell LJ. Weight and body composition changes in first semester college freshmen. 1st Annual Boshell Diabetes and Metabolic Diseases Research Day. Auburn, AL, March 2008.

 

Funding

5P20GM103528-09 NIH/NIGMS Centers of Biomedical Research Excellence. “Mentoring Obesity and Diabetes Research in Louisiana”.
March 2015- July 2015
Role: Project Principal Investigator

1 F32 DK098918-01A1 NIH Ruth L. Kirschstein National Research Service Award: F32. “Role of UCP1 in the Inter-organ Lipid Cycle Engaged by Dietary Methionine Restriction”.
January 2014- February 2015
Role: Principal Investigator

7-13-MI-05 American Diabetes Association Mentor-Based Postdoctoral Minority Fellowship Award. Role of UCP1 in the Inter-organ Lipid Cycle Engaged by Dietary Methionine Restriction.
October 2013- December 2013.
Role: Postdoctoral Fellow

3T32DK064584 NIH Ruth L. Kirschstein National Research Service Award: Institutional Research Training Grant (T32). “Obesity: From Genes to Man”, Pennington Biomedical Research Center
October 2012- September 2013.
Role: Postdoctoral Fellow

University Peak of Excellence graduate research fellowship in Cellular and Molecular Biosciences, Auburn University, AL.
August 2008-August 2009
Role: Graduate Research Assistant

Service

Ad-Hoc Manuscript Reviewer

  1. Obesity
  2. Annals of the New York Academy of Sciences
  3. Journal of Endocrinology
  4. Comparative Biochemistry and Physiology

 

Awards and Honors

Keystone Symposia Future of Science Fund Scholarship (Travel Grant)
Keystone Symposia – Beige and Brown Fat: Basic Biology and Novel Therapeutics
April 2015

Outstanding Postdoctoral Poster Presentation
The Boshell Diabetes and Metabolic Diseases 6th Annual Research Day
March 2013

Outstanding Doctoral Student
Auburn University
2011-2012

Outstanding Graduate Student Oral Presentation
Graduate Symposium: Auburn University Research Week
April 2012

Outstanding Graduate Student Oral Presentation
The Boshell Diabetes and Metabolic Diseases 5th Annual Research Day
March 2012